Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6682199 | 0.99 | ENPP2 (0.40) | ENPP2LOXL2CFDHTR6AURKB | |
| SCHEMBL6677091 | 0.84 | ENPP2 (0.44) | ENPP2LOXL2CFDHTR6AURKB | |
| Hydrochloric Acid SCHEMBL6675347 | 0.82 | ENPP2 (0.43) | ENPP2LOXL2CFDHTR6AURKB | |
| SCHEMBL6677797 | 0.81 | MAPT (0.44) | ENPP2LOXL2CFDHTR6AURKB | |
| SCHEMBL6676819 | 0.80 | LOXL2 (0.46) | ENPP2LOXL2CFDHTR6AURKB | |
| Hydrochloric Acid SCHEMBL6678204 | 0.80 | MAPT (0.43) | ENPP2LOXL2CFDHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6677448 | 0.79 | LOXL2 (0.45) | ENPP2LOXL2CFDHTR6AURKB | |
| SCHEMBL5080879 | 0.77 | LOXL2 (0.49) | ENPP2LOXL2CFDHTR6AURKB | |
| SCHEMBL27823913 | 0.76 | LOXL2 (0.49) | ENPP2LOXL2CFDHTR6AURKB | |
| Hydrochloric Acid SCHEMBL7875006 | 0.75 | LOXL2 (0.47) | ENPP2LOXL2CFDHTR6AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |