Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6678204 | 0.99 | MAPT (0.43) | MAPTENPP2LOXL2SIGMAR1GRIN2D | |
| SCHEMBL6677091 | 0.88 | ENPP2 (0.44) | MAPTENPP2LOXL2SIGMAR1GRIN2D | |
| Hydrochloric Acid SCHEMBL6675347 | 0.87 | ENPP2 (0.43) | ENPP2LOXL2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL6676819 | 0.81 | LOXL2 (0.46) | ENPP2LOXL2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL6676930 | 0.81 | ENPP2 (0.41) | ENPP2LOXL2SIGMAR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6677448 | 0.80 | LOXL2 (0.45) | ENPP2LOXL2SIGMAR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6682199 | 0.80 | ENPP2 (0.40) | ENPP2LOXL2SIGMAR1CFDHTR6 | |
| SCHEMBL5080879 | 0.78 | LOXL2 (0.49) | ENPP2LOXL2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL10824122 | 0.77 | KMT2A (0.62) | MAPTKMT2AEPHX1 | |
| SCHEMBL27823913 | 0.77 | LOXL2 (0.49) | ENPP2LOXL2SIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |