SCHEMBL6677013

SCHEMBL6677013

Cc1ccc2cc3ccccc3cc2c1CN

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.57
ALDH1A1 P00352 8/20 0.42
HSD17B10 Q99714 5/20 0.42
CYP1A2 P05177 4/20 0.42
KDM4E B2RXH2 3/20 0.42
GAA P10253 3/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 2/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CYP2A6 P11509 3/20 0.39
TSHR P16473 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP1B1 Q16678 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 3/20 0.38
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HBB P68871 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4351690 0.82 ALDH1A1 (0.60) HTR2AALDH1A1HSD17B10CYP1A2KDM4E
SCHEMBL17697793 0.81 CYP1A2 (0.42) HTR2AALDH1A1HSD17B10CYP1A2KDM4E
Hydrochloric Acid SCHEMBL6251241 0.81 ALDH1A1 (0.58) HTR2AALDH1A1HSD17B10CYP1A2KDM4E
SCHEMBL15353131 0.79 HTR2A (0.59) HTR2AALDH1A1HSD17B10CYP1A2KDM4E
SCHEMBL28294546 0.76 CYP1A2 (0.38) HTR2AALDH1A1HSD17B10CYP1A2KDM4E
SCHEMBL5750258 0.75 ALDH1A1 (0.57) HTR2AALDH1A1HSD17B10CYP1A2KDM4E
SCHEMBL460085 0.74 CYP1A2 (0.64) ALDH1A1HSD17B10CYP1A2KDM4EGAA
SCHEMBL29726949 0.74 CYP1A2 (0.64) ALDH1A1HSD17B10CYP1A2KDM4EGAA
SCHEMBL28294547 0.74 CYP1A2 (0.36) HTR2AALDH1A1HSD17B10CYP1A2KDM4E
SCHEMBL2384515 0.73 HTR2A (1.00) HTR2AALDH1A1HSD17B10CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3113857-A1 CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES Waters Technologies Corporation (US) 2017-01-11 EP disclosed
WO-2015134317-A9 CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES WATERS TECHNOLOGIES CORPORATION (US) 2016-08-04 WO disclosed
WO-2015134317-A1 CHROMOTOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES WATERS TECHNOLOGIES CORPORATION (US) 2015-09-11 WO disclosed
WO-2004035600-A1 METHOD OF MANUFACTURING LABELLED OLIGONUCLEOTIDE CONJUGATES CHEMOGENIX GMBH (DE) 2004-04-29 WO disclosed
EP-0465371-B1 Chemical cartridge for protective respiratory mask INST RECHEN SANTE ET EN SECURI (CA) 1995-12-13 EP disclosed
EP-0465371-A2 Chemical cartridge for protective respiratory mask INSTITUT DE RECHERCHE EN SANTE ET EN SECURITE DU TRAVAIL DU QUEBEC (CA) 1992-01-08 EP disclosed