SCHEMBL28294547

SCHEMBL28294547

Cc1ccc2cc3ccccc3cc2c1CC(O)CO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 1/20 0.36
CYP2D6 P10635 2/20 0.36
MEN1 O00255 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
UGT2B7 P16662 1/20 0.34
SLC6A2 P23975 2/20 0.33
CYP2A6 P11509 2/20 0.33
TSHR P16473 2/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
MAPT P10636 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17697793 0.80 CYP1A2 (0.42) CYP1A2KDM4EALDH1A1HSD17B10HPGD
SCHEMBL28294546 0.78 CYP1A2 (0.38) CYP1A2KDM4EALDH1A1HSD17B10HPGD
SCHEMBL6677013 0.74 HTR2A (0.57) CYP1A2KDM4EALDH1A1HSD17B10HPGD
SCHEMBL6176510 0.69 TSHR (0.47) CYP1A2KDM4EALDH1A1HSD17B10HPGD
SCHEMBL14277051 0.69 HTR2A (0.54) CYP1A2KDM4EALDH1A1HSD17B10HPGD
SCHEMBL28519170 0.68 HTR2A (0.55) CYP1A2CYP2A6CYP3A4HTR2AHTR2C
Adonitol SCHEMBL27869815 0.68 ALDH1A1 (0.45) CYP1A2KDM4EALDH1A1HSD17B10HPGD
SCHEMBL8330046 0.68 HTR1A (0.35) CYP1A2KDM4EALDH1A1CYP2D6MEN1
SCHEMBL5517520 0.68 ALDH1A1 (0.37) CYP1A2KDM4EALDH1A1HSD17B10HPGD
SCHEMBL787068 0.68 CYP1A2 (0.46) CYP1A2KDM4EALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109765758-A Siliceous bottom 罗门哈斯电子材料有限责任公司 2019-05-17 CN disclosed