Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6251241 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL6249203 | 0.83 | TSHR (0.58) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL16042478 | 0.83 | TSHR (0.58) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL6677013 | 0.82 | HTR2A (0.57) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL607362 | 0.81 | CYP1A2 (0.56) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL29489290 | 0.81 | TSHR (0.56) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL29489289 | 0.81 | TSHR (0.56) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| Potassium SCHEMBL29978462 | 0.81 | TSHR (0.56) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL1538534 | 0.79 | TSHR (0.54) | ALDH1A1KDM4EMAPTGAATAAR1 | |
| SCHEMBL821213 | 0.79 | TSHR (0.54) | ALDH1A1KDM4EMAPTGAATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002002503-A1 | PROCESS FOR PREPARATION OF TERBINAFINE AND ITS HYDROCHLORIDE AS AN ANTIFUNGAL AGENT | CHEMTECH RESEARCH INCORPORATION (KR) | 2002-01-10 | — | — | WO | claimed |
| WO-2020264499-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| EP-3655398-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | Phenex-FXR GmbH (DE) | 2020-05-27 | — | — | EP | disclosed |
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
| CN-110914248-A | LXR modulators containing amines or (thio) amides | 菲尼克斯-FXR股份有限公司 | 2020-03-24 | — | — | CN | disclosed |
| WO-2019016269-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2019-01-24 | — | — | WO | disclosed |
| EP-2657214-B1 | PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL | MITSUBISHI GAS CHEMICAL CO (JP) | 2017-02-15 | — | — | EP | disclosed |
| EP-3113857-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | Waters Technologies Corporation (US) | 2017-01-11 | — | — | EP | disclosed |
| CN-104055756-B | The derivant of naftifine hydrochloride, Preparation method and use | 中国科学院上海药物研究所 | 2016-10-05 | — | — | CN | disclosed |
| WO-2015134317-A9 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2016-08-04 | — | — | WO | disclosed |
| US-6452001-B2 | 1,4-DIAZEPINE-2-ONE DERIVATIVES AS NEUROKININ ANTAGONIST | HOFFMANN-LA ROCHE INC. | 2002-09-17 | — | — | US | disclosed |
| US-20020010174-A1 | Diazapane derivatives useful as antagonists of neurokinin 1 receptor and methods for their formation | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | US | disclosed |
| WO-2002002503-A1 | PROCESS FOR PREPARATION OF TERBINAFINE AND ITS HYDROCHLORIDE AS AN ANTIFUNGAL AGENT | CHEMTECH RESEARCH INCORPORATION (KR) | 2002-01-10 | — | — | WO | disclosed |
| WO-2001090083-A1 | 1,4-DIAZEPAN-2,5-DIONE DERIVATIVES AND THEIR USE AS NK-1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |
| WO-2001077064-A1 | METHOD FOR THE PREPARATION OF (E)-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHALENEMETHANAMINE (TERBINAFINE) | SLOVAKOFARMA A.S. (SK) | 2001-10-18 | — | — | WO | disclosed |
| EP-1077962-A2 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by The Secretary, Department of Health and Human Services (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058517-A2 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-11-18 | — | — | WO | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |
| EP-0617002-A1 | Process for preparing naphthalenepolycarboxylic acids | BAYER AG (DE) | 1994-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | ALDH1A1 2016/4885KDM4E 2569/4885MAPT 3356/4885 |
| US-20020010174-A1 | Diazapane derivatives useful as antagonists of neurokinin 1 receptor and methods for their formation | BDKRB2, NPSR1, BDKRB1 | ALDH1A1 1088/4885KDM4E 3134/4885MAPT 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.