Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677943 | 0.88 | KMT2A (0.45) | GHSRMAPTFFAR4PLAUPLAT | |
| SCHEMBL6672598 | 0.86 | HTR6 (0.42) | HTR6 | |
| SCHEMBL6817411 | 0.85 | BRAF (0.40) | HTR6MAPTSCN9ABRAFFFAR1 | |
| SCHEMBL6823530 | 0.84 | BRAF (0.38) | MAPTBRAFFFAR1FFAR4TP53 | |
| SCHEMBL6817421 | 0.84 | PLA2G7 (0.44) | — | |
| SCHEMBL6819746 | 0.83 | FFAR4 (0.40) | MAPTFFAR1FFAR4TP53 | |
| SCHEMBL6819870 | 0.83 | FFAR4 (0.38) | HTR6MAPTFFAR1FFAR4TP53 | |
| SCHEMBL6820791 | 0.83 | FFAR4 (0.36) | MAPTBRAFFFAR1FFAR4TP53 | |
| SCHEMBL6817431 | 0.82 | FFAR4 (0.51) | GHSRMAPTFFAR1FFAR4TP53 | |
| SCHEMBL6820305 | 0.82 | FFAR4 (0.38) | MAPTFFAR1FFAR4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043369-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |