Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 5/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820791 | 0.92 | FFAR4 (0.36) | BRAFMAPTTP53PLA2G7FFAR4 | |
| SCHEMBL6820451 | 0.87 | FFAR4 (0.38) | BRAFMAPTTSHRTP53CCR2 | |
| SCHEMBL6820305 | 0.86 | FFAR4 (0.38) | MAPTTP53PLA2G7FFAR4FFAR1 | |
| SCHEMBL6820782 | 0.86 | SMN1; SMN2 (0.33) | MAPTTP53LMNAHTT | |
| SCHEMBL6824643 | 0.86 | UTS2R (0.35) | MEN1KMT2AALDH1A1LMNAALPL | |
| SCHEMBL6820345 | 0.85 | MEN1 (0.38) | BRAFMAPTTP53CCR2PLA2G7 | |
| SCHEMBL6677066 | 0.84 | HTR6 (0.46) | BRAFMAPTTP53FFAR4FFAR1 | |
| SCHEMBL6821099 | 0.84 | UTS2R (0.33) | — | |
| SCHEMBL6823531 | 0.84 | UTS2R (0.34) | — | |
| SCHEMBL6817411 | 0.83 | BRAF (0.40) | BRAFMAPTTSHRTP53CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |