Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.39 |
| ▸ | PTPRF | P10586 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247258 | 0.89 | ALDH1A1 (0.56) | ALDH1A1GAAMAPKAPK2 | |
| SCHEMBL6675952 | 0.86 | CYP2C9 (0.45) | ALDH1A1GAATDP1NAMPTMAPT | |
| SCHEMBL6690531 | 0.83 | ALDH1A1 (0.39) | ALDH1A1GAATDP1PTPN1MAPKAPK2 | |
| SCHEMBL6681076 | 0.81 | MAPK1 (0.45) | ALDH1A1GAATDP1MAPKAPK2MAPT | |
| SCHEMBL6674829 | 0.81 | PTPN1 (0.38) | ALDH1A1GAATDP1PTPN1RORC | |
| SCHEMBL6674831 | 0.80 | PTPN1 (0.39) | ALDH1A1GAATDP1PTPN1RORC | |
| SCHEMBL6690522 | 0.79 | ALDH1A1 (0.37) | ALDH1A1GAATDP1PTPN1RORC | |
| SCHEMBL20869029 | 0.79 | ALDH1A1 (0.48) | ALDH1A1GAATDP1PTPN1PTPN2 | |
| SCHEMBL30101803 | 0.79 | ALDH1A1 (0.48) | ALDH1A1GAATDP1PTPN1PTPN2 | |
| SCHEMBL6679066 | 0.78 | ALDH1A1 (0.54) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |