Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681445 | 0.73 | KMT2A (0.48) | KMT2ARAB9ANPC1HTTALDH1A1 | |
| SCHEMBL1720197 | 0.67 | NPC1 (0.67) | HPGDPOLBRAB9ANPC1EPHX1 | |
| SCHEMBL7592068 | 0.66 | HTT (0.70) | KMT2ARAB9ANPC1CYP1A2CYP2D6 | |
| SCHEMBL6629295 | 0.66 | TP53 (0.44) | HPGDPOLBKMT2ARAB9ANPC1 | |
| N-O-Tolylbenzamide SCHEMBL3223289 | 0.66 | HPGD (1.00) | HPGDPOLBKMT2ARAB9ANPC1 | |
| SCHEMBL4403976 | 0.65 | ITGB1 (0.55) | HPGDPOLBRAB9ANPC1HTT | |
| SCHEMBL8177930 | 0.65 | KMT2A (0.71) | HPGDPOLBKMT2ARAB9ANPC1 | |
| SCHEMBL665339 | 0.65 | RAB9A (0.75) | HPGDPOLBRAB9ANPC1EPHX1 | |
| SCHEMBL5647518 | 0.64 | KMT2A (0.48) | HPGDKMT2ARAB9ANPC1HTT | |
| SCHEMBL2096115 | 0.64 | NPC1 (0.62) | HPGDPOLBKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |