Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659356 | 0.87 | HPGD (0.64) | NPC1RAB9AHPGDALDH1A1POLB | |
| Urethane SCHEMBL10734055 | 0.85 | RAB9A (0.56) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL1952694 | 0.84 | NLRP3 (0.62) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL2096115 | 0.84 | NPC1 (0.62) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL69360 | 0.82 | NPC1 (0.71) | NPC1RAB9AHPGDALDH1A1ALOX12 | |
| SCHEMBL8045695 | 0.82 | HPGD (0.63) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL1023162 | 0.82 | HPGD (0.50) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL30593915 | 0.82 | NPC1 (0.71) | NPC1RAB9AHPGDALDH1A1ALOX12 | |
| SCHEMBL4821320 | 0.81 | HPGD (0.49) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL8448713 | 0.81 | HPGD (0.49) | NPC1RAB9AHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630717-B1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | claimed |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-07-07 | — | — | US | claimed |
| US-20200148631-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-05-14 | — | — | US | claimed |
| EP-3630717-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | Council of Scientific and Industrial Research (IN) | 2020-04-08 | — | — | EP | claimed |
| CN-110698416-B | Preparation method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-03-20 | — | — | CN | claimed |
| CN-110698416-A | Preparation method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-01-17 | — | — | CN | claimed |
| WO-2018216036-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-11-29 | — | — | WO | claimed |
| CN-103562198-B | There is muscarinic receptor antagonist and the compound of beta 2-adrenergic receptor agonists activity | 奇斯药制品公司 | 2016-08-24 | — | — | CN | claimed |
| CN-103562198-A | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMA SPA | 2014-02-05 | — | — | CN | claimed |
| US-20040102521-A1 | Excitatory amino acid receptor modulators | ELI LILLY AND COMPANY | 2004-05-27 | — | — | US | claimed |
| CN-112020493-B | Method for producing urethane and method for producing isocyanate | 旭化成株式会社 | 2023-04-21 | — | — | CN | disclosed |
| EP-3630717-B1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | disclosed |
| CN-110546135-B | Method for producing isocyanate | 旭化成株式会社 | 2021-12-14 | — | — | CN | disclosed |
| CN-112020493-A | Method for producing carbamate and method for producing isocyanate | 旭化成株式会社 | 2020-12-01 | — | — | CN | disclosed |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-07-07 | — | — | US | disclosed |
| US-4260781-A | Process for the manufacture of carbamates | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4258201-A | CATALYTIC CARBONYLATION OF PRIMARY OR SECONDARY AMINES WITH CARBON MONOXIDE AND ALCOHOLS | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4242520-A | ONE-STEP CARBONYLATION OF AMINES IN THE PRESENCE OF A DISULFIDE | HALCON RESEARCH & DEVELOPMENT CORPORATION (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0014103-A2 | Improved process for the manufacture of carbamates | THE HALCON SD GROUP, INC. (US) | 1980-08-06 | — | — | EP | disclosed |
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102521-A1 | Excitatory amino acid receptor modulators | GRM1, GRM2, GRIN1 | NPC1 1241/4885RAB9A 2180/4885HPGD 3529/4885 |
| US-20200148631-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | TYR, DDC, ALK | NPC1 4157/4885RAB9A 3127/4885HPGD 4663/4885 |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | ALK, DDC, TYR | NPC1 4118/4885RAB9A 3122/4885HPGD 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.