Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522852 | 0.98 | FAAH (0.46) | FAAHRELACA2MEN1ALDH1A1 | |
| SCHEMBL8637397 | 0.98 | FAAH (0.46) | FAAHRELACA2MEN1ALDH1A1 | |
| SCHEMBL4910681 | 0.98 | FAAH (0.46) | FAAHRELACA2MEN1ALDH1A1 | |
| SCHEMBL966696 | 0.98 | FAAH (0.46) | FAAHRELACA2MEN1ALDH1A1 | |
| SCHEMBL1751774 | 0.98 | FAAH (0.46) | FAAHRELACA2MEN1ALDH1A1 | |
| SCHEMBL424437 | 0.93 | CA1 (0.38) | FAAHRELACA2MEN1ALDH1A1 | |
| SCHEMBL423936 | 0.83 | — | — | |
| SCHEMBL27884330 | 0.80 | FAAH (0.41) | FAAHRELACA2CA1 | |
| SCHEMBL5313006 | 0.80 | FAAH (0.41) | FAAHRELACA2CA1 | |
| SCHEMBL5532020 | 0.76 | CA2 (0.48) | FAAHRELACA2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004181-B3 | ANDROGEN RECEPTOR MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND ANDROGEN RECEPTOR-ASSOCIATED DISEASES | UNIV CALIFORNIA (US) | 2023-05-24 | — | — | EP | claimed |
| EP-2004181-B1 | ANDROGEN RECEPTOR MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND ANDROGEN RECEPTOR-ASSOCIATED DISEASES | UNIV CALIFORNIA (US) | 2016-02-24 | — | — | EP | claimed |
| CN-103554006-A | Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson's disease | FOURNIER LAB SA | 2014-02-05 | — | — | CN | claimed |
| US-20120232070-A1 | Use of Indole Derivatives as Nurr-1 Activators for the Application Thereof as a Medicament for the Treatment of Parkinson's Disease | LABORATOIRES FOURNIER SA (FR) | 2012-09-13 | — | — | US | claimed |
| EP-2475642-A1 | USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE APPLICATION THEREOF AS A MEDICAMENT FOR THE TREATMENT OF PARKINSON'S DISEASE | Laboratoires Fournier S.A. (FR) | 2012-07-18 | — | — | EP | claimed |
| CN-102596906-A | Use of indole derivatives as NURR-1 activators as agents for the treatment of Parkinson's disease | FOURNIER LAB SA | 2012-07-18 | — | — | CN | claimed |
| CN-102236257-A | Coloring photosensitive composition, manufacture method for color filter, color filter, and liquid crystal display device | FUJI PHOTO FILM CO LTD | 2011-11-09 | — | — | CN | claimed |
| WO-2011030068-A1 | USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE APPLICATION THEREOF AS A MEDICAMENT FOR THE TREATMENT OF PARKINSON'S DISEASE | LABORATOIRES FOURNIER SA (FR) | 2011-03-17 | — | — | WO | claimed |
| US-7767665-B2 | 3-[6-(4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propionic acid, having an excellent apoptosis inhibitory and Macrophage migration inhibitory factor (MIF) binding effects, used for preventing and/or treating cancers, AIDS, cardiovascular, neurodegeneartive, bone, kidney and liver disoders | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-03 | — | — | US | claimed |
| US-20100190830-A1 | (3-Amino-1,2,3,4-Tetrahydro-9H-Carbazol-9-yl)-Acetic Acid Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-07-29 | — | — | US | claimed |
| CN-1446200-A | Aryl phenycyclopropyl sulfide derivatives and their use as cell adhesion-ichibiting anti-inflammatory and immune-suppressive agents | ABBOTT LAB (US) | 2003-10-01 | — | — | CN | claimed |
| US-20030181496-A1 | Pyrrole derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2003-09-25 | — | — | US | claimed |
| EP-0946202-B1 | CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2003-09-10 | — | — | EP | claimed |
| CN-1100777-C | N-heterocyclic derivatives as NOS inhibitor | BERLEX LAB (US) | 2003-02-05 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| CN-1252799-A | N-heterocyclic derivatives as NOS inhibitor | BERLEX LAB (US) | 2000-05-10 | — | — | CN | claimed |
| US-5306609-A | With nondiffusive coupler and acyl acetamide coupler of specified formulae; high color density, color image fastness | FUJI PHOTO FILM CO., LTD. (JP) | 1994-04-26 | — | — | US | claimed |
| CN-1081438-A | Imdazole derivatives and preparation method thereof and the application on therapeutics | FOURNIER IND & SANTE (FR) | 1994-02-02 | — | — | CN | claimed |
| US-4640940-A | CONTACT LENSES | LOCTITE CORPORATION (US) | 1987-02-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232070-A1 | Use of Indole Derivatives as Nurr-1 Activators for the Application Thereof as a Medicament for the Treatment of Parkinson's Disease | NCOR1, NR0B1, MTNR1A | FAAH 3040/4885RELA 435/4885CA2 4693/4885 |
| US-20100190830-A1 | (3-Amino-1,2,3,4-Tetrahydro-9H-Carbazol-9-yl)-Acetic Acid Derivatives | PTGDR, PTGER1, PTGIR | FAAH 251/4885RELA 771/4885CA2 810/4885 |
| US-20030181496-A1 | Pyrrole derivatives | NCOA1, PKD1, NR3C2 | FAAH 1975/4885RELA 1000/4885CA2 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.