SCHEMBL6677360

SCHEMBL6677360

c1ccc(P(Cc2ccc3ccccc3c2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 1/20 0.50
KMT2A Q03164 1/20 0.44
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
MC4R P32245 2/20 0.41
MC5R P33032 2/20 0.41
SIGMAR1 Q99720 1/20 0.41
ALOX5 P09917 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
MC3R P41968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682306 0.84 CYP1A2 (0.50) CYP1A2CYP2A6KMT2AHTR2AHTR2C
SCHEMBL27841453 0.81 CYP1A2 (0.49) CYP1A2CYP2A6KMT2AHTR2AHTR2C
SCHEMBL4827020 0.80 CYP3A4 (0.43) ALDH1A1CYP3A4HSD17B10
SCHEMBL15516632 0.79 LOXL2 (0.40) CYP2A6SIGMAR1ALDH1A1CYP3A4HSD17B10
SCHEMBL9510685 0.79 CYP1A2 (0.58) CYP1A2CYP2A6KMT2AHTR2AHTR2C
SCHEMBL230856 0.75 TDP1 (0.43) CYP2A6HTR2AALDH1A1CYP3A4HSD17B10
SCHEMBL11762652 0.75 CYP2A6 (0.59) CYP1A2CYP2A6KMT2AHTR2AHTR2C
SCHEMBL7769248 0.74 MAPT (0.50) KMT2A
SCHEMBL29620392 0.74 TAAR1 (0.44) KMT2AALDH1A1CYP3A4HRH3
SCHEMBL8860405 0.73 AGXT (0.46) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004048463-A1 POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS PARODI FABRIZIO (IT) 2004-06-10 WO claimed
EP-3524646-A1 IONIC COMPOUND, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DIODE LG Chem, Ltd. (KR) 2019-08-14 EP disclosed
WO-2004048463-A1 POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS PARODI FABRIZIO (IT) 2004-06-10 WO disclosed