Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381509 | 0.76 | LTA4H (0.57) | — | |
| SCHEMBL6677360 | 0.74 | CYP1A2 (0.50) | KMT2A | |
| SCHEMBL7775442 | 0.73 | MAPT (0.52) | MAPTNQO1CETPKMT2AMEN1 | |
| SCHEMBL7773470 | 0.73 | MAPT (0.52) | MAPTNQO1TTRCETPPOLB | |
| SCHEMBL12770651 | 0.72 | PTGS2 (0.48) | MAPTLMNASMN1; SMN2 | |
| SCHEMBL4827020 | 0.72 | CYP3A4 (0.43) | — | |
| SCHEMBL7773493 | 0.71 | ALOX5 (0.58) | MAPTKMT2AMEN1LMNAPLAU | |
| SCHEMBL10546824 | 0.70 | LTA4H (0.57) | MAPTSMN1; SMN2 | |
| SCHEMBL7809875 | 0.69 | MAPT (0.47) | MAPTNQO1KMT2AMEN1LMNA | |
| SCHEMBL4899610 | 0.69 | HTR7 (0.39) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839818-B1 | Optically active diphosphines, transition metal complex containing the same, and process for producing an optically active compound using the complex | TAKASAGO PERFUMERY CO LTD (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5789609-A | CATALYST FOR ASSYMETRIC SYNTHESIS, REACTION OF AN A-CYANO ESTER AND A VINYL KETONE TO PRODUCE AN OXO CYANO ESTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0839818-A1 | Optically active diphosphine, transition metal complex containing the same, and process for producing optically active compound using the complex | Takasago International Corporation (JP) | 1998-05-06 | — | — | EP | disclosed |