Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918244 | 0.79 | ELANE (0.39) | TDP1POLBALDH1A1TSHRELANE | |
| SCHEMBL7945467 | 0.79 | — | — | |
| SCHEMBL1291212 | 0.78 | KDM4E (0.43) | LMNAKDM4ECYP3A4TDP1ALOX12 | |
| SCHEMBL29043932 | 0.76 | P2RX7 (0.31) | HSP90AA1 | |
| SCHEMBL782969 | 0.76 | MEN1 (0.37) | TSHRADRA1AHSP90AA1 | |
| SCHEMBL10552758 | 0.76 | ALDH1A1 (0.38) | LMNAKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL28560571 | 0.76 | ELANE (0.41) | TDP1MAPTELANEADRA2AADRA1A | |
| SCHEMBL10917585 | 0.74 | KDM4E (0.34) | KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL28808109 | 0.74 | CYP3A4 (0.39) | LMNAKDM4ECYP3A4TDP1ALOX12 | |
| Methylamine SCHEMBL536416 | 0.74 | KDM4E (0.41) | LMNAKDM4ECYP3A4TDP1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130992-A | Nitrogen-containing heterocyclic compound having kinase inhibiting activity, preparation method and application | UNIV SOOCHOW | 2015-12-09 | — | — | CN | disclosed |
| CN-104876941-A | Fused tricyclic compound and applications thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-09-02 | — | — | CN | disclosed |
| CN-103450204-A | Pyrrole [2,1-f][1,2,4] triazine compound, and preparation method and purpose thereof | SHANGHAI INST MATERIA MEDICA | 2013-12-18 | — | — | CN | disclosed |
| CN-101880283-B | Kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2012-07-18 | — | — | CN | disclosed |
| CN-101880283-A | Novel Kinase Inhibitors | BRISTOL MYERS SQUIBB CO | 2010-11-10 | — | — | CN | disclosed |
| CN-1993361-B | Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER PHARMACEUTICALS CORP | 2010-05-26 | — | — | CN | disclosed |
| CN-1993361-A | Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER PHARMACEUTICALS CORP (US) | 2007-07-04 | — | — | CN | disclosed |
| CN-1315833-C | Azaindole kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-05-16 | — | — | CN | disclosed |
| CN-1269911-C | Active dye compound | UNIV OF NORTH CAROLINA (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1681818-A | Azaindole kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2005-10-12 | — | — | CN | disclosed |
| US-6239276-B1 | STABILIZER | CYTEC TECHNOLOGY CORPORATION | 2001-05-29 | — | — | US | disclosed |
| EP-1089984-A1 | NON-YELLOWING PARA-TERTIARY-ALKYL PHENYL SUBSTITUTED TRIAZINE AND PYRIMIDINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067226-A1 | NON-YELLOWING PARA-TERTIARY-ALKYL PHENYL SUBSTITUTED TRIAZINE AND PYRIMIDINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 1999-12-29 | — | — | WO | disclosed |
| CN-1229405-A | Novel acetamide derivatives and protease inhibitors | NIPPON KAYAKU KK (JP) | 1999-09-22 | — | — | CN | disclosed |
| US-5604181-A | Pyrimidine derivatives herbicides | AGREVO UK LIMITED (GB) | 1997-02-18 | — | — | US | disclosed |
| US-5502028-A | Herbicidal pyrimidinyl or triazinyl haloacetic acid derivatives | SCHERING AGROCHEMICALS LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |
| EP-0660829-A1 | PYRIMIDINE DERIVATIVE HERBICIDES | AgrEvo UK Limited (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005644-A1 | PYRIMIDINE DERIVATIVE HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-03-17 | — | — | WO | disclosed |
| EP-0575404-A1 | HERBICIDES | AgrEvo UK Limited (GB) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016511-A1 | HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |