Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698034 | 0.85 | SIGMAR1 (0.31) | KMT2AMEN1SIGMAR1 | |
| SCHEMBL20195364 | 0.81 | KCNH2 (0.35) | TSHRGAASIGMAR1ALDH1A1CYP2C9 | |
| SCHEMBL6673681 | 0.81 | ALDH1A1 (0.39) | LMNAPOLBKMT2AGAAMEN1 | |
| SCHEMBL27392966 | 0.81 | PIK3CA (0.39) | LMNAPOLBKMT2AGAAMEN1 | |
| SCHEMBL1259047 | 0.79 | KCNH2 (0.38) | LMNAKMT2AMEN1SIGMAR1ALDH1A1 | |
| SCHEMBL20919908 | 0.79 | KCNH2 (0.38) | LMNAKMT2AMEN1SIGMAR1ALDH1A1 | |
| SCHEMBL14492990 | 0.79 | MAPT (0.39) | LMNAPKMTSHRPOLBKMT2A | |
| SCHEMBL5244482 | 0.78 | ALDH1A1 (0.44) | LMNATSHRPOLBKMT2AGAA | |
| SCHEMBL3779703 | 0.78 | RECQL (0.31) | — | |
| SCHEMBL20979464 | 0.78 | KMO (0.55) | LMNATSHRPOLBKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334865-A1 | DDR2 INHIBITORS AND METHODS OF USING | WASHINGTON UNIVERSITY (US) | 2017-11-23 | — | — | US | claimed |
| WO-2016070024-A1 | DDR2 INHIBITORS AND METHODS OF USING | WASHINGTON UNIVERSITY (US) | 2016-05-06 | — | — | WO | claimed |
| CN-107056849-B | Preparation method of α -2, 6-dideoxy glucose-O-glucoside protected by total acetyl | 华东师范大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-107056849-A | A kind of full acetyl group protects the preparation method of the dideoxy glucose O glucosides of α 2,6 | 华东师范大学 | 2017-08-18 | — | — | CN | disclosed |
| EP-1066813-B1 | Dental adhesive composition | SHOFU KK (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-6583197-B1 | Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent | KABUSHIKI KAISHA SHOFU (JP) | 2003-06-24 | — | — | US | disclosed |
| EP-1066813-A2 | Dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2001-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334865-A1 | DDR2 INHIBITORS AND METHODS OF USING | DDR2, DDR1, DDRGK1 | LMNA 792/4885PKM 3940/4885TSHR 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.