SCHEMBL6677524

SCHEMBL6677524

NOB(ON)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 3/20 0.46
ORAI2 Q96SN7 3/20 0.46
ORAI3 Q9BRQ5 3/20 0.46
TRPV6 Q9H1D0 3/20 0.46
CA4 P22748 3/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41
CA7 P43166 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA5B Q9Y2D0 2/20 0.41
ENPP2 Q13822 1/20 0.41
PCSK9 Q8NBP7 1/20 0.41
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
TRPM2 O94759 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4928266 0.85 ORAI1 (0.39) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL8396426 0.83 KDM4E (0.47) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL28230966 0.79 ORAI1 (0.34) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL28430844 0.76 CA4 (0.48) CA4CA7CA14ENPP2ALDH1A1
SCHEMBL28363887 0.76 CA1 (0.40) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL16549328 0.72 ENPP2 (0.48) CA4CA6CA5ACA14CA5B
SCHEMBL56106 0.72 TRPV6 (0.50) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL263612 0.71 ORAI1 (0.52) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL309077 0.71 CA4 (0.48) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL2744416 0.71 ORAI1 (0.46) ORAI1ORAI2ORAI3TRPV6CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574335-A Photo-curing resin, high-toughness adhesive product and preparation method thereof 万华化学集团股份有限公司 2026-02-27 CN claimed
CN-113136020-A Water-based polyurethane polymer and preparation method thereof, single-component water-based polyurethane waterproof coating and preparation method and application thereof 万华化学集团股份有限公司 2021-07-20 CN claimed
CN-121574335-A Photo-curing resin, high-toughness adhesive product and preparation method thereof 万华化学集团股份有限公司 2026-02-27 CN disclosed
CN-113136020-B Water-based polyurethane polymer and preparation method thereof, single-component water-based polyurethane waterproof coating and preparation method and application thereof 万华化学集团股份有限公司 2022-08-05 CN disclosed
CN-113136020-A Water-based polyurethane polymer and preparation method thereof, single-component water-based polyurethane waterproof coating and preparation method and application thereof 万华化学集团股份有限公司 2021-07-20 CN disclosed
US-10617706-B2 Compounds for cancer chemotherapeutic sensitization REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2020-04-14 US disclosed
US-20190240244-A1 COMPOUNDS FOR CANCER CHEMOTHERAPEUTIC SENSITIZATION REGENTS OF THE UNIVERSITY OF MINNESOTA 2019-08-08 US disclosed
US-8048680-B2 Holographic sensor SMART HOLOGRAMS LIMITED (GB) 2011-11-01 US disclosed
EP-1187676-B1 APPARATUS FOR CONDUCTING AN ASSAY PROVALIS DIAGNOSTICS LTD (GB) 2004-10-06 EP disclosed
US-6677158-B2 DETECTION OF GLYCATED HEMOGLOBIN; OBTAIN SAMPLE, INCUBATE WITH PAD, ELUTE, INCUBATE WITH MEMBRANE, MONITOR INTENSITY OF HEMOGLOBIN COLOR, DETERMINE THE RATION OF GLYCATED TO NON-GLYCATED HEMOGLOBIN EXOCELL INC. 2004-01-13 US disclosed
US-20020164811-A1 Novel method for measurement of glycated hemoglobin by a rapid strip test procedure EXOCELL, INC. 2002-11-07 US disclosed
EP-1187676-A1 APPARATUS, INSTRUMENT AND DEVICE FOR CONDUCTING AN ASSAY Provalis Diagnostics Limited (GB) 2002-03-20 EP disclosed
WO-2000076663-A1 APPARATUS, INSTRUMENT AND DEVICE FOR CONDUCTING AN ASSAY PROVALIS DIAGNOSTICS LIMITED (GB) 2000-12-21 WO disclosed
US-5763203-A Immobilization and separation of cells and other particles SINVENT AS (NO) 1998-06-09 US disclosed
EP-0688430-B1 IMMOBILISATION AND SEPARATION OF CELLS AND OTHER PARTICLES SINVENT AS (NO) 1997-05-28 EP disclosed
EP-0688430-A1 IMMOBILISATION AND SEPARATION OF CELLS AND OTHER PARTICLES SINVENT AS (NO) 1995-12-27 EP disclosed
WO-1994020858-A1 IMMOBILISATION AND SEPARATION OF CELLS AND OTHER PARTICLES SINVENT A/S (NO) 1994-09-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10617706-B2 Compounds for cancer chemotherapeutic sensitization ABCC1, MCL1, ABCC3 ORAI1 4230/4885ORAI2 4231/4885ORAI3 2719/4885
US-20190240244-A1 COMPOUNDS FOR CANCER CHEMOTHERAPEUTIC SENSITIZATION ABCC1, MCL1, ABCC3 ORAI1 4230/4885ORAI2 4231/4885ORAI3 2719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.