Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | SI | P14410 | 3/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154349 | 0.83 | GUSB (0.60) | MGAMGAASIMGAM2S1PR1 | |
| SCHEMBL6677778 | 0.81 | MGAM (0.51) | MGAMGAASIMGAM2S1PR1 | |
| SCHEMBL3564976 | 0.73 | MCL1 (0.50) | GSTP1BCL2L1MCL1MEN1KMT2A | |
| SCHEMBL3832934 | 0.71 | GAA (0.71) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL6153476 | 0.70 | NOTUM (0.56) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL6155089 | 0.70 | PIK3CD (0.48) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL4674930 | 0.70 | MEN1 (0.70) | GAAMAPTL3MBTL1ALOX5GSTP1 | |
| SCHEMBL6677701 | 0.69 | ABL1 (0.41) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL6682394 | 0.69 | ALDH1A1 (0.53) | MGAMGAASIMGAM2S1PR1 | |
| SCHEMBL1842452 | 0.69 | MEN1 (0.59) | GAAMAPTL3MBTL1ALOX5GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |