Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678138 | 0.88 | MEN1 (0.45) | MEN1KMT2AHTTCYP3A4TSHR | |
| SCHEMBL6679652 | 0.83 | CES2 (0.36) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL6682474 | 0.83 | MEN1 (0.43) | MEN1KMT2AHTTCYP3A4TSHR | |
| SCHEMBL6681184 | 0.74 | MEN1 (0.38) | MEN1KMT2AHTTCYP3A4TSHR | |
| SCHEMBL6678308 | 0.70 | AKR1C1 (0.34) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL6677414 | 0.68 | KMT2A (0.40) | MEN1KMT2AHTTCYP3A4TSHR | |
| SCHEMBL28890126 | 0.66 | AKR1C1 (0.46) | KMT2AHTTTSHRALDH1A1ALOX15 | |
| SCHEMBL9690243 | 0.66 | KMT2A (0.53) | MEN1KMT2AHTTCYP3A4TSHR | |
| SCHEMBL830804 | 0.66 | MEN1 (0.53) | MEN1KMT2AHTTTSHRADAM17 | |
| SCHEMBL349195 | 0.65 | MEN1 (0.56) | MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |