Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678308 | 0.86 | AKR1C1 (0.34) | AKR1C1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL28890126 | 0.84 | AKR1C1 (0.46) | CES2CES1AKR1C1OPRM1OPRL1 | |
| SCHEMBL6677902 | 0.83 | MEN1 (0.47) | MEN1KMT2AHTTTSHRALOX15 | |
| SCHEMBL6680771 | 0.79 | AKR1C1 (0.37) | AKR1C1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL6677414 | 0.76 | KMT2A (0.40) | AKR1C1MEN1KMT2AHCAR3HCAR2 | |
| SCHEMBL6677871 | 0.75 | AKR1C1 (0.34) | CES1AKR1C1MEN1KMT2AHCAR3 | |
| SCHEMBL29031878 | 0.74 | ALDH1A1 (0.44) | CES2CES1MEN1KMT2AHTT | |
| SCHEMBL6676563 | 0.73 | ATM (0.37) | AKR1C1MEN1KMT2AHCAR3HCAR2 | |
| SCHEMBL6677394 | 0.72 | AKR1C1 (0.37) | AKR1C1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL5614157 | 0.71 | HCAR3 (0.36) | AKR1C1OPRM1OPRL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |