Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682346 | 0.90 | KDM4E (0.49) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6674164 | 0.87 | ALDH1A1 (0.48) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6673765 | 0.83 | ALDH1A1 (0.51) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1894678 | 0.79 | ALDH1A1 (0.66) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6670350 | 0.78 | KMT2A (0.53) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14133155 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6678019 | 0.76 | MAPT (0.51) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11157838 | 0.75 | ALDH1A1 (0.67) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6673517 | 0.74 | ALDH1A1 (0.86) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6689636 | 0.74 | HSD17B10 (0.53) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |