Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678055 | 0.90 | ALDH1A1 (0.54) | KDM4ESMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL6678019 | 0.85 | MAPT (0.51) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6677923 | 0.82 | CCNE1 (0.53) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6674164 | 0.81 | ALDH1A1 (0.48) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6684415 | 0.78 | SMN1; SMN2 (0.54) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6689636 | 0.77 | HSD17B10 (0.53) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6673765 | 0.77 | ALDH1A1 (0.51) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6683539 | 0.77 | ADORA3 (0.54) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6683533 | 0.76 | KDM4E (0.50) | KDM4ESMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6681136 | 0.76 | MEN1 (0.57) | KDM4EMAPTMAPK1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |