Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679944 | 0.92 | GRM2 (0.32) | GRM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL6675986 | 0.91 | GRM2 (0.32) | GRM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL6675633 | 0.90 | GRM2 (0.35) | GRM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL6675985 | 0.89 | GRM2 (0.31) | GRM2 | |
| SCHEMBL6679129 | 0.88 | KDM4E (0.31) | GRM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL6684402 | 0.88 | ADRA2A (0.31) | GRM2 | |
| SCHEMBL6681139 | 0.87 | KDM4E (0.31) | GRM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL6686115 | 0.86 | RXRA (0.32) | GRM2 | |
| SCHEMBL6682282 | 0.85 | SLC9A1 (0.33) | KDM4EMAPT | |
| SCHEMBL6682109 | 0.83 | STAT5B (0.36) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |