Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6684024 | 0.99 | PTGIR (0.48) | PTGIRSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL6680859 | 0.86 | PTGIR (0.51) | PTGIRCYP1A2CYP2C19ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6676156 | 0.85 | PTGIR (0.50) | PTGIRCYP1A2CYP2C19ADRA2AADRA2B | |
| SCHEMBL6678263 | 0.84 | PTGIR (0.49) | PTGIRSLC6A2SLC6A4SLC6A3CYP1A2 | |
| Hydrochloric Acid SCHEMBL7245284 | 0.83 | ALDH1A1 (0.49) | PTGIRSLC6A2SLC6A4SLC6A3ADRA2A | |
| SCHEMBL6675654 | 0.76 | PTGIR (0.49) | PTGIR | |
| SCHEMBL6677062 | 0.76 | ADRA2A (0.53) | PTGIRADRA2AADRA2BADRA2CHTT | |
| SCHEMBL6675147 | 0.76 | PTGIR (0.49) | PTGIRCYP1A2CYP2C19ADRA2AKMT2A | |
| Hydrochloric Acid SCHEMBL6680559 | 0.75 | PTGIR (0.48) | PTGIRADRA2A | |
| Hydrochloric Acid SCHEMBL6676217 | 0.75 | PTGIR (0.48) | PTGIRADRA2AADRA2BADRA2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |