Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804598 | 0.81 | LTB4R2 (0.40) | SLC6A2TAAR1SLC6A4MAOASLC6A3 | |
| SCHEMBL6809999 | 0.78 | SYK (0.41) | ITGB1ITGA4BRS3 | |
| SCHEMBL6539936 | 0.74 | ANPEP (0.51) | SLC6A2TAAR1SLC6A4MAOASLC6A3 | |
| SCHEMBL30309077 | 0.74 | BCAT2 (0.59) | HNF4ACA1CA2 | |
| SCHEMBL10775490 | 0.72 | TAAR1 (0.55) | SLC6A2TAAR1SLC6A4MAOASLC6A3 | |
| Hydrochloric Acid SCHEMBL6680440 | 0.72 | ALDH1A1 (0.48) | SLC6A2TAAR1HNF4ABCL2L1 | |
| Hydrochloric Acid SCHEMBL6680444 | 0.72 | ALDH1A1 (0.48) | SLC6A2TAAR1HNF4ABCL2L1 | |
| SCHEMBL29226029 | 0.72 | HNF4A (0.56) | HNF4ACA1CA2CA9 | |
| SCHEMBL30153392 | 0.72 | HNF4A (0.56) | HNF4ACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6800406 | 0.71 | TAAR1 (0.39) | SLC6A2TAAR1SLC6A4MAOASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |