SCHEMBL6796384

SCHEMBL6796384

O=C(NCc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccn1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMO Q99835 1/20 0.55
TRPV1 Q8NER1 2/20 0.53
KDR P35968 1/20 0.53
MTTP P55157 7/20 0.52
APOB P04114 1/20 0.52
GAA P10253 1/20 0.50
GRM4 Q14833 3/20 0.49
TLR7 Q9NYK1 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7606603 0.91 CES1 (0.55) SMOTRPV1KDRMTTPAPOB
SCHEMBL6793033 0.90 TRPV1 (0.52) SMOTRPV1KDRMTTPAPOB
SCHEMBL6794587 0.90 SMO (0.55) SMOKDRMTTPAPOBGAA
SCHEMBL6492242 0.89 GCGR (0.49) SMOTRPV1KDRMTTPGRM4
SCHEMBL6799242 0.89 CHRNB2 (0.59) SMOKDRGAAGRM4
SCHEMBL6794304 0.88 GRM4 (0.55) KDRGRM4
SCHEMBL6788420 0.87 MTTP (0.57) TRPV1KDRMTTPAPOBGAA
SCHEMBL6793810 0.87 KDR (0.52) KDRGRM4
SCHEMBL6793626 0.87 NAMPT (0.56) SMOTRPV1KDRMTTPAPOB
SCHEMBL6799904 0.86 MTTP (0.50) SMOMTTPAPOBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US claimed
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 SMO 2094/4885TRPV1 3714/4885KDR 3180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.