SCHEMBL6679360

SCHEMBL6679360

Brc1ccc2c(Br)c3ccc(Br)cc3c(Br)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.41
CYP2A6 P11509 3/20 0.41
JAK2 O60674 3/20 0.39
PIM1 P11309 2/20 0.39
METAP2 P50579 1/20 0.39
CHEK1 O14757 1/20 0.39
AURKA O14965 1/20 0.39
DAPK3 O43293 1/20 0.39
PRKD3 O94806 1/20 0.39
MAP4K4 O95819 1/20 0.39
PAK4 O96013 1/20 0.39
ABL1 P00519 1/20 0.39
NTRK1 P04629 1/20 0.39
CSF1R P07333 1/20 0.39
RET P07949 1/20 0.39
MET P08581 1/20 0.39
PDGFRB P09619 1/20 0.39
FGFR1 P11362 1/20 0.39
PDGFRA P16234 1/20 0.39
PRKACA P17612 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30132916 1.00 GPR84 (0.41) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL1165315 1.00 GPR84 (0.41) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL1823011 0.92 MEN1 (0.44) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL29010739 0.91 GPR84 (0.40) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL16158369 0.80 CYP2A6 (0.47) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL8993461 0.79 CYP2A6 (0.39) CYP2A6ALDH1A1TDP1
SCHEMBL20356135 0.78 ALOX15 (0.37) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL13616030 0.75 BCL2 (0.45) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL31049230 0.75 BCL2 (0.50) GPR84CYP2A6JAK2PIM1METAP2
SCHEMBL598418 0.73 ALOX15 (0.42) GPR84CYP2A6JAK2PIM1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004053018-A1 ELECTROLUMINESCENT DEVICES XIE SHUANG (CA) 2004-06-24 WO disclosed
US-20030215667-A1 Electroluminescent devices ELIGHT CORPORATION (VG) 2003-11-20 US disclosed