SCHEMBL8993461

SCHEMBL8993461

Brc1c2ccc2c(Br)c2ccc12

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.39
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28511 0.82 ALDH1A1 (0.44) CYP2A6ALDH1A1TDP1GAA
SCHEMBL29352635 0.82 ALDH1A1 (0.44) CYP2A6ALDH1A1TDP1GAA
SCHEMBL30132916 0.79 GPR84 (0.41) CYP2A6ALDH1A1TDP1
SCHEMBL1165315 0.79 GPR84 (0.41) CYP2A6ALDH1A1TDP1
SCHEMBL6679360 0.79 GPR84 (0.41) CYP2A6ALDH1A1TDP1
SCHEMBL7915432 0.79 POLB (0.42) CYP2A6ALDH1A1TDP1GAA
SCHEMBL8993488 0.74
SCHEMBL28563878 0.74 CYP1A2 (0.41) CYP2A6ALDH1A1TDP1GAA
SCHEMBL31502572 0.74 CYP1A2 (0.42) CYP2A6ALDH1A1TDP1GAA
SCHEMBL31502573 0.74 CYP1A2 (0.42) CYP2A6ALDH1A1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5552508-A Difunctional bitricyclodecatriene monomers UNIVERSITY OF MICHIGAN, THE BOARD OF REGENTS (US) 1996-09-03 US disclosed