Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763403 | 0.74 | SLC6A4 (0.44) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL10763892 | 0.72 | MTNR1A (0.42) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL9353539 | 0.72 | MTNR1A (0.42) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL1488230 | 0.72 | MTNR1A (0.42) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL11402564 | 0.72 | MAOA (0.52) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL24066716 | 0.72 | MTNR1A (0.42) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL43675 | 0.72 | MTNR1A (0.42) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL6309709 | 0.72 | MTNR1A (0.46) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL6679558 | 0.72 | MEN1 (0.47) | MTNR1AMTNR1BGAAMEN1KMT2A | |
| SCHEMBL19544761 | 0.71 | SLC6A4 (0.42) | MTNR1AMTNR1BGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041799-A1 | 5- (SUBSTITUTED PHENYL) -THIADIAZOLIDINE-3-ONES AND THEIR USE AS PTP1B | ASTRAZENECA AB (SE) | 2004-05-21 | — | — | WO | disclosed |