Phosphoric Acid

Phosphoric Acid

SCHEMBL6679867

Nc1cc(N)c(O)cc1O.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
GAA P10253 7/20 0.41
MAPT P10636 5/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
KDM4E B2RXH2 3/20 0.41
PKM P14618 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSD17B10 Q99714 5/20 0.40
ALOX15 P16050 4/20 0.40
CYP3A4 P08684 2/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ALOX12 P18054 3/20 0.37
HPGD P15428 2/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PTK2 Q05397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL9626680 1.00 ALDH1A1 (0.41) ALDH1A1GAAMAPTMEN1KMT2A
Phosphoric Acid SCHEMBL9627690 0.92 ALDH1A1 (0.42) ALDH1A1GAAMAPTMEN1KMT2A
Phosphoric Acid SCHEMBL9627549 0.92 ALDH1A1 (0.42) ALDH1A1GAAMAPTMEN1KMT2A
Pyrophosphoric Acid SCHEMBL6679860 0.85 BLM (0.46) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL106886 0.85 ALDH1A1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL3182704 0.82 ALDH1A1 (0.48) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL2675947 0.82 ALDH1A1 (0.48) ALDH1A1GAAMAPTMEN1KMT2A
Sulfuric Acid SCHEMBL8659769 0.78 ALDH1A1 (0.52) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL2026680 0.76 PTK2 (0.57) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL9626683 0.75 INPPL1 (0.52) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805173-B1 Method for production of polybenzazole TOYO BOSEKI (JP) 2004-10-27 EP disclosed
EP-0805173-A1 Method for production of polybenzazole Toyo Boseki Kabushiki Kaisha (JP) 1997-11-05 EP disclosed
US-5142021-A In dehydrating acid solution containing polyphosphoric acid and methanesulfonic acid THE DOW CHEMICAL COMPANY (US) 1992-08-25 US disclosed
US-5138020-A PHOSPHATE SALTS OF MONOMERS FOR PBZ AND THEIR USE IN PREPARING PBZ POLYMERS THE DOW CHEMICAL COMPANY (US) 1992-08-11 US disclosed
EP-0393559-A2 Phosphate salts of monomers for PBZ and their use in preparing PBZ polymers THE DOW CHEMICAL COMPANY (US) 1990-10-24 EP disclosed