Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 7/20 | 0.48 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.39 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL41565 | 1.00 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10348271 | 0.97 | PTK2 (0.53) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28456008 | 0.97 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL106886 | 0.96 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL28229778 | 0.96 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL28190785 | 0.93 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL2675947 | 0.93 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Water SCHEMBL27493672 | 0.93 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2146037 | 0.90 | PTK2 (0.53) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Methyl Alcohol SCHEMBL27532918 | 0.90 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122082149-A | Ultraviolet-resistant PBO fiber with excellent mechanical properties and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-120134776-A | Preparation method of high-strength multilayer composite fabric | 江苏佩浦高分子科技有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119859105-A | Preparation method of 4, 6-diaminoresorcinol hydrochloride crystal | 中国石油化工股份有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-119684604-A | Flexible temperature-resistant PBO polymer and preparation process thereof | 中蓝晨光化工研究设计院有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119640624-A | High-strength PBO composite insulating paper and preparation method thereof | 山东非金属材料研究所 | 2025-03-18 | — | — | CN | claimed |
| CN-119640581-A | Preparation method of modified PBO fiber toughening agent for well cementation under high-frequency alternating injection and production conditions | 西南石油大学 | 2025-03-18 | — | — | CN | claimed |
| CN-119593096-A | Ultraviolet radiation resistant PBOH fiber and preparation method thereof | 哈尔滨工业大学 | 2025-03-11 | — | — | CN | claimed |
| CN-119571491-A | High-strength high-modulus PBO fiber and preparation method thereof | 中国石油化工股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119571492-A | Ultraviolet aging resistant high-strength high-modulus PBO fiber and preparation method thereof | 中国石油化工股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119194654-B | Preparation method of low-dielectric PBO fiber | 山东非金属材料研究所 | 2025-02-18 | — | — | CN | claimed |
| CN-103880767-A | Preparation method for 2-(p-formylchloropropyl)-5-amino-6-hydroxyl benzoxazole | HARBIN INST OF TECHNOLOGY | 2014-06-25 | — | — | CN | claimed |
| CN-103709404-A | PBO (poly(p-phenylene-2,6-benzobisoxazole)) copolycondensation modification method | CHONGQING INST GREEN & INTELLIGENT TECHNOLOGY CAS | 2014-04-09 | — | — | CN | claimed |
| US-20130298933-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL (FR) | 2013-11-14 | — | — | US | claimed |
| CN-103160950-A | Preparation method for ultraviolet-resistant PBO fibers | KINGFA SCIENCE & TECHNOLOGY CO | 2013-06-19 | — | — | CN | claimed |
| CN-103013113-A | Preparation method of graphene/PBO polymer | HARBIN INST OF TECHNOLOGY | 2013-04-03 | — | — | CN | claimed |
| CN-103014901-A | Preparation method of graphene/PBO (Poly-P-Phenylene Benzobisoxazazole) composite fiber | HARBIN INST OF TECHNOLOGY | 2013-04-03 | — | — | CN | claimed |
| CN-102992312-A | Preparation method of graphene monomer complex | HARBIN INST OF TECHNOLOGY | 2013-03-27 | — | — | CN | claimed |
| CN-102296376-B | Production method of poly-p-phenylene benzodioxazole fibers | SINOSELEN HI TECH CO LTD | 2013-01-09 | — | — | CN | claimed |
| US-20100300472-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | claimed |
| CN-1583752-A | Synthesis of benzoxazole | UNIV HARBIN POLYTECHNIC (CN) | 2005-02-23 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100300472-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | KRT18, TUBB4A, TUBB4B | GAA 3877/4885HSP90AA1 404/4885CA2 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.