Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.67 |
| ▸ | MALT1 | Q9UDY8 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683372 | 0.87 | PTGS1 (0.69) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6680929 | 0.85 | PTGS2 (0.60) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6684663 | 0.85 | PTGS1 (0.62) | PTGS1PTGS2MALT1L3MBTL1APP | |
| SCHEMBL4031131 | 0.83 | PTGS2 (0.81) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6683996 | 0.83 | PTGS2 (0.81) | PTGS1PTGS2MALT1L3MBTL1MAPT | |
| SCHEMBL4032188 | 0.82 | PTGS1 (0.72) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6685276 | 0.81 | PTGS2 (0.54) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6680320 | 0.80 | PTGS1 (0.58) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL4026247 | 0.79 | PTGS1 (0.76) | PTGS1PTGS2MALT1L3MBTL1ALDH1A1 | |
| SCHEMBL6686713 | 0.78 | PTGS2 (0.81) | PTGS1PTGS2MALT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |