SCHEMBL6680469

SCHEMBL6680469

Cc1cc(C)c(N)c(Cc2cc(C)cc(C)c2N)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP1A2 P05177 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP7 P55210 1/20 0.44
KDM4E B2RXH2 4/20 0.43
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
ATP4A P20648 1/20 0.38
ATP4B P51164 1/20 0.38
AMY1A P0DUB6 1/20 0.38
HSPA5 P11021 1/20 0.38
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8371085 0.87 ALDH1A1 (0.41) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15
SCHEMBL9864156 0.84 ALDH1A1 (0.34) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15
SCHEMBL28870156 0.83 TAAR1 (0.41) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15
SCHEMBL2038792 0.83 ALDH1A1 (0.52) ALDH1A1KDM4ETSHRTP53CYP3A4
SCHEMBL817061 0.83 KDM4E (0.42) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15
SCHEMBL28870093 0.82 MPO (0.40) ALDH1A1MAPTATP4AATP4BHTT
SCHEMBL30961933 0.81 KDM4E (0.45) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15
SCHEMBL30961935 0.81 KDM4E (0.45) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15
SCHEMBL30961934 0.81 KDM4E (0.45) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15
SCHEMBL29241765 0.81 KDM4E (0.45) ALDH1A1HIF1AHSD17B10CYP1A2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019172227-A1 ADHESIVE COMPOSITION タツタ電線株式会社 2019-09-12 WO disclosed
EP-0878740-B1 Radiation sensitive polymer composition TORAY INDUSTRIES (JP) 2004-11-10 EP disclosed
US-6090525-A PHOTOSENSITIVE POLYIMIDE COATING AGENT COMPOSITION WITH BOTH GOOD VISCOSITY STABILITY AT ROOM TEMPERATURE WITH LAPSE OF TIME AND GOOD PHOTOSENSITIVE PERFORMANCE TORAY INDUSTRIES, INC. (JP) 2000-07-18 US disclosed
EP-0878740-A1 Radiation sensitive polymer composition TORAY INDUSTRIES, INC. (JP) 1998-11-18 EP disclosed
EP-0274354-B1 PHOTOSTRUCTURABLE POLYIMIDE COMPOSITIONS, POLYIMIDES ON THE BASIS OF BENZHYDROL TETRACARBOXYLIC ACID AND THEIR FABRICATION CIBA-GEIGY AG (CH) 1992-01-08 EP disclosed
US-4851506-A Photostructurable polyimide mixtures CIBA-GEIGY CORPORATION (US) 1989-07-25 US disclosed
EP-0252883-A1 Coated material containing a radiation-sensitive polyimide layer with special diaminodiphenyl methane units CIBA-GEIGY AG (CH) 1988-01-13 EP disclosed
US-4208507-A LOW TEMPERATUER AND MECHANICAL PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed