SCHEMBL9864156

SCHEMBL9864156

Cc1cc(C)c(N)c(Cc2cc(C(C)C)cc(C)c2N)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP7 P55210 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
ADRA1D P25100 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
ATP4A P20648 1/20 0.32
ATP4B P51164 1/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9863794 0.93 ALDH1A1 (0.39) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL10781624 0.92 FABP3 (0.35) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL10782824 0.86 FABP3 (0.38) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL10781032 0.85 ALDH1A1 (0.36) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL6680469 0.84 ALDH1A1 (0.44) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL9864040 0.76 ALDH1A1 (0.40) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL1183197 0.76 ALDH1A1 (0.52) ALDH1A1HIF1AHSD17B10KDM4EADRA2A
SCHEMBL9864155 0.75 FABP4 (0.44) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL9863694 0.74 POLB (0.44) CYP1A2HTR1DHTR1B
Hydrochloric Acid SCHEMBL28293183 0.74 ALDH1A1 (0.50) ALDH1A1HIF1AHSD17B10KDM4EADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5051310-A Textured polyurethane molded articles having multiple sheet layers BASF AKTIENGESELLSCHAFT (DE) 1991-09-24 US disclosed
US-4698371-A REACTION INJECTION MOLDING BASF AKTIENGESELLSCHAFT (DE) 1987-10-06 US disclosed