Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405841 | 0.82 | PTGS2 (0.47) | PTGS2PNMTP2RY6MALT1ABCB1 | |
| SCHEMBL6683777 | 0.82 | PTGS2 (0.41) | PTGS2PNMTP2RY6GABRA1GABRB2 | |
| SCHEMBL6409858 | 0.82 | PTGS2 (0.47) | PTGS2PNMTP2RY6MALT1ABCB1 | |
| SCHEMBL6682272 | 0.80 | PTGS1 (0.46) | PTGS2GABRA1GABRB2PTGS1 | |
| SCHEMBL31006601 | 0.73 | PNMT (0.48) | PTGS2PNMTP2RY6 | |
| SCHEMBL6684596 | 0.71 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6407893 | 0.70 | PTGS2 (0.47) | PTGS2P2RY6PTGS1TDP1 | |
| SCHEMBL6406175 | 0.70 | PTGS2 (0.47) | PTGS2P2RY6PTGS1TDP1 | |
| SCHEMBL6681124 | 0.70 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL6407324 | 0.68 | FFAR1 (0.42) | PTGS2P2RY6PTGS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274700-B1 | DIHYDROBENZOPYRANS, DIHYDROBENZOTHIOPYRANS, AND TETRAHYDROQUINOLINES FOR THE TREATMENT OF COX-2-MEDIATED DISORDERS | PHARMACIA CORP (US) | 2004-11-17 | — | — | EP | claimed |