Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412233 | 0.83 | PTGS1 (0.47) | PTGS1PTGS2FFAR4FFAR1PPARA | |
| SCHEMBL6683777 | 0.83 | PTGS2 (0.41) | PTGS1PTGS2FFAR4FFAR1GABRA1 | |
| SCHEMBL6406536 | 0.83 | PTGS1 (0.47) | PTGS1PTGS2FFAR4FFAR1PPARA | |
| SCHEMBL6680877 | 0.80 | PTGS2 (0.45) | PTGS1PTGS2GABRA1GABRB2 | |
| SCHEMBL6684596 | 0.72 | PTGS2 (0.46) | PTGS1PTGS2PPARAPPARDPPARG | |
| SCHEMBL6437666 | 0.71 | TDP1 (0.48) | PTGS1PTGS2FFAR4FFAR1GABRA1 | |
| SCHEMBL6681124 | 0.71 | PTGS2 (0.41) | PTGS1PTGS2 | |
| SCHEMBL1519550 | 0.70 | TP53 (0.47) | PTGS1PTGS2FFAR4FFAR1BCL2L1 | |
| SCHEMBL6408673 | 0.69 | ALOX5 (0.44) | FFAR4PPARAPPARG | |
| SCHEMBL6407685 | 0.69 | ALOX5 (0.44) | FFAR4PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274700-B1 | DIHYDROBENZOPYRANS, DIHYDROBENZOTHIOPYRANS, AND TETRAHYDROQUINOLINES FOR THE TREATMENT OF COX-2-MEDIATED DISORDERS | PHARMACIA CORP (US) | 2004-11-17 | — | — | EP | claimed |