Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875031 | 0.89 | TSHR (0.55) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL10695276 | 0.85 | TSHR (0.59) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL10695280 | 0.85 | TSHR (0.59) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL8855359 | 0.85 | TSHR (0.55) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL27847930 | 0.81 | TSHR (0.54) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL18638414 | 0.81 | TSHR (0.50) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL3292782 | 0.81 | TSHR (0.75) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL5715396 | 0.80 | LOXL2 (0.55) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL11135899 | 0.80 | CHRM2 (0.57) | TSHRKCNJ1KCNH2ALDH1A1LMNA | |
| SCHEMBL5661624 | 0.79 | TSHR (0.61) | TSHRLOXL2KCNJ1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879043-B1 | Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2018-01-30 | — | — | US | disclosed |
| US-9034850-B2 | Gonadotropin releasing hormone receptor antagonist, preparation method thereof and pharmaceutical composition comprising the same | SK CHEMICALS CO., LTD. (KR) | 2015-05-19 | — | — | US | disclosed |
| US-8673586-B2 | Compounds that interact with kinases | ALCHEMIA LIMITED (AU) | 2014-03-18 | — | — | US | disclosed |
| US-20130137661-A1 | Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same | SK CHEMICALS CO. LTD. (KR) | 2013-05-30 | — | — | US | disclosed |
| US-20130011852-A1 | COMPOUNDS THAT INTERACT WITH KINASES | ALCHEMIA LIMITED (AU) | 2013-01-10 | — | — | US | disclosed |
| US-20080176815-A1 | Compounds that interact with kinases | ALCHEMIA LIMITED (AU) | 2008-07-24 | — | — | US | disclosed |
| US-7291623-B2 | Compounds that interact with kinases | ALCHEMIA LIMITED (AU) | 2007-11-06 | — | — | US | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0824099-B1 | Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient | MITSUI CHEMICALS INC (JP) | 2001-11-07 | — | — | EP | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5965774-A | CONTROLLING PLANT DISEASES AGAINST BOTRYTIS CINEREA, POWDERY MILDEW, PYRICULARIA ORYZAE OF RICE PLANT | MITSUI CHEMICALS, INC. (JP) | 1999-10-12 | — | — | US | disclosed |
| US-5914344-A | Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient | MITSUI CHEMICALS, INC. (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0824099-A1 | Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137661-A1 | Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same | GNRHR, GHRHR, LHCGR | TSHR 42/4885LOXL2 4017/4885KCNJ1 2548/4885 |
| US-20080176815-A1 | Compounds that interact with kinases | MAP3K6, MAP3K20, MAP4K2 | TSHR 3479/4885LOXL2 3230/4885KCNJ1 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.