Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679750 | 0.78 | NQO2 (0.50) | NQO2TSHRLMNAIDO1MEN1 | |
| SCHEMBL6677280 | 0.77 | LMNA (0.34) | LMNAMEN1KMT2APOLBHPGD | |
| SCHEMBL7247902 | 0.76 | NQO2 (0.46) | NQO2TSHRLMNAIDO1MEN1 | |
| SCHEMBL6676761 | 0.73 | POLB (0.35) | NQO2TSHRLMNAPOLBGAA | |
| SCHEMBL6681403 | 0.73 | NQO2 (0.56) | NQO2TSHRLMNAIDO1MEN1 | |
| SCHEMBL6674498 | 0.70 | NQO2 (0.53) | NQO2TSHRLMNAIDO1MEN1 | |
| SCHEMBL21680877 | 0.70 | NQO2 (0.57) | NQO2TSHRLMNAIDO1MEN1 | |
| SCHEMBL6674376 | 0.69 | NQO2 (0.52) | NQO2TSHRLMNAIDO1MEN1 | |
| SCHEMBL19509465 | 0.69 | NQO2 (0.52) | NQO2TSHRLMNAIDO1MEN1 | |
| SCHEMBL4597216 | 0.69 | NQO2 (0.60) | NQO2TSHRLMNAIDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |