Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681242 | 1.00 | CYP3A4 (0.53) | CYP3A4LMNAMAPK1CYP2C19ALDH1A1 | |
| SCHEMBL10952917 | 0.84 | ALDH1A1 (0.43) | CYP3A4ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1286158 | 0.84 | LMNA (0.50) | LMNAMAPK1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL2879779 | 0.84 | CYP3A4 (0.59) | CYP3A4LMNAMAPK1CYP2C19ALDH1A1 | |
| SCHEMBL9230354 | 0.84 | CYP3A4 (0.55) | CYP3A4LMNACYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL16322805 | 0.84 | LMNA (0.50) | LMNAMAPK1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7878160 | 0.82 | CYP3A4 (0.53) | CYP3A4LMNAMAPK1CYP2C19ALDH1A1 | |
| SCHEMBL11775539 | 0.81 | CYP3A4 (0.49) | CYP3A4LMNAMAPK1CYP2C19ALDH1A1 | |
| SCHEMBL10676559 | 0.81 | CYP3A4 (0.51) | CYP3A4LMNAMAPK1CYP2C19ALDH1A1 | |
| SCHEMBL2879781 | 0.81 | CYP3A4 (0.56) | CYP3A4LMNAMAPK1CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948490-A1 | PROCESS FOR THE PREPARATION OF 2-IMINO-5-PHENYL-4-OXAZOLIDINONE AND ITS INTERMEDIATES | Abbott Laboratories (US) | 1999-10-13 | — | — | EP | claimed |
| WO-1998022450-A1 | PROCESS FOR THE PREPARATION OF 2-IMINO-5-PHENYL-4-OXAZOLIDINONE AND ITS INTERMEDIATES | ABBOTT LABORATORIES (US) | 1998-05-28 | — | — | WO | claimed |
| US-5677463-A | Process for the preparation of 2-imino-5-phenyl-4 oxazolidinone and its intermediates | ABBOTT LABORATORIES (US) | 1997-10-14 | — | — | US | claimed |
| US-5523459-A | OXIDIZING ALPHA-HYDROXYCARBOXYLIC ACID ESTER WITH MOLECULAR OXYGEN IN GASEOUS PHASE IN PRESENCE OF COPPER PHOSPHATE | UBE INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | claimed |
| EP-0673914-A2 | Preparation of alpha-keto acid ester | UBE INDUSTRIES, LTD. (JP) | 1995-09-27 | — | — | EP | claimed |
| CN-114849679-A | Solid superacid supported catalyst and preparation method of beta-phenethyl alcohol | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-107089912-B | Method for selectively catalyzing and synthesizing mandelate compound by metallocene complex | 湖南大学 | 2020-10-30 | — | — | CN | disclosed |
| EP-1205464-B1 | Production method of 2-cyclohexyl-2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof | SUMIKA FINE CHEMICALS CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6777576-B2 | NOVEL 2-(2'-CYCLOHEXEN-1'-YL)-2-HYDROXY- 2-PHENYLACETIC ACID ESTER OBTAINED BY REACTING CYCLOHEXENE AND BENZOYLFORMIC ACID ESTER IN PRESENCE OF A LEWIS ACID IS HYDROLYZED AND REDUCED TO GIVE 2-CYCLOHEXYL-2-HYDROXY-2-PHENYLACETIC ACID | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20030013911-A1 | Production method of 2-cyclohexyl- 2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-0951283-A4 | NOVEL ARACHIDONIC ACID METABOLITE, 16-HETE | UNIV VERMONT (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-1205464-A2 | Production method of 2-cyclohexyl-2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-5677463-A | Process for the preparation of 2-imino-5-phenyl-4 oxazolidinone and its intermediates | ABBOTT LABORATORIES (US) | 1997-10-14 | — | — | US | disclosed |
| EP-0409234-B1 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | CHISSO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5164112-A | Optical activity, ferroelectric, short response times | CHISSO CORPORATION (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0409234-A2 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | Chisso Corporation (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0140454-B1 | PROCESS FOR FORMING ESTERS OF GLYOXYLIC ACIDS | STAUFFER CHEMICAL COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| EP-0206772-A2 | Herbicidal aryloxybenzeneacetic acid derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4524214-A | OXIDATION OF AN ORGANOGLYCOLATE ESTER WITH A HYPOHALIDE | STAUFFER CHEMICAL COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0140454-A2 | Process for forming esters of glyoxylic acids | STAUFFER CHEMICAL COMPANY (US) | 1985-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013911-A1 | Production method of 2-cyclohexyl- 2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof | HCAR2, HACL2, HADHB | CYP3A4 182/4885LMNA 4131/4885MAPK1 3735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.