Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879779 | 0.93 | CYP3A4 (0.59) | CYP3A4SRCCYP2C19ALDH1A1TSHR | |
| SCHEMBL10646849 | 0.87 | CYP3A4 (0.53) | CYP3A4SRCCYP2C19ALDH1A1TSHR | |
| SCHEMBL9230354 | 0.82 | CYP3A4 (0.55) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7878160 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6681237 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6681242 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10676559 | 0.79 | CYP3A4 (0.51) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5325702 | 0.79 | CYP3A4 (0.51) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5994366 | 0.79 | CYP3A4 (0.51) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL14619857 | 0.79 | CYP3A4 (0.51) | CYP3A4CYP2C19ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153860-B2 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | claimed |
| US-20040116429-A1 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF SE (DE) | 2004-06-17 | — | — | US | claimed |
| US-7709637-B2 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| US-7465735-B2 | crop protection agents for controlling harmful fungi; improved activity; 6-chloro-2-(N'-isopropylidene-hydrazino)-5-(2,4,6-trifluorophenyl)pyrimidine-4-yl]-((S)-1-trifluoromethylethyl)amine; against Septoria Leaf Blotch of Wheat, Net Blotch of Barley and Mildew of Cucumber | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-16 | — | — | US | disclosed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | disclosed |
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | GYPSER ANDREAS | 2007-06-28 | — | — | US | disclosed |
| US-20070088026-A1 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | METAVANTE CORPORATION | 2007-04-19 | — | — | US | disclosed |
| US-7153860-B2 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | disclosed |
| US-20060148764-A1 | 5-phenypyrimidines their preparation compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | disclosed |
| US-20040116429-A1 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF SE (DE) | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | CBR1, CBR3, NTPCR | CYP3A4 574/4885SRC 2465/4885CYP2C19 794/4885 |
| US-20060148764-A1 | 5-phenypyrimidines their preparation compositions comprising them and their use | CBR1, CBR3, NT5C | CYP3A4 590/4885SRC 2019/4885CYP2C19 873/4885 |
| US-20070088026-A1 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | DPYD, CBR3, RNGTT | CYP3A4 169/4885SRC 3888/4885CYP2C19 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.