SCHEMBL668135

SCHEMBL668135

C[C@H](NC(=O)[C@@H](N)CS)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.52
▸ SLC7A11 Q9UPY5 1/20 0.52
▸ MME P08473 8/20 0.50
▸ ACE P12821 2/20 0.50
▸ CPA1 P15085 1/20 0.50
▸ ACE2 Q9BYF1 1/20 0.50
▸ ENPEP Q07075 2/20 0.42
▸ FNTA P49354 2/20 0.40
▸ FNTB P49356 2/20 0.40
▸ PGGT1B P53609 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668134 1.00 PTGS1 (0.52) PTGS1SLC7A11MMEACECPA1
SCHEMBL29476451 1.00 PTGS1 (0.52) PTGS1SLC7A11MMEACECPA1
SCHEMBL30358358 1.00 PTGS1 (0.52) PTGS1SLC7A11MMEACECPA1
SCHEMBL11325497 1.00 PTGS1 (0.52) PTGS1SLC7A11MMEACECPA1
SCHEMBL31118495 0.96 PTGS1 (0.48) PTGS1SLC7A11MMEACECPA1
SCHEMBL31118358 0.96 PTGS1 (0.48) PTGS1SLC7A11MMEACECPA1
SCHEMBL29850032 0.96 PTGS1 (0.48) PTGS1SLC7A11MMEACECPA1
SCHEMBL31118396 0.96 PTGS1 (0.48) PTGS1SLC7A11MMEACECPA1
SCHEMBL31118408 0.96 PTGS1 (0.48) PTGS1SLC7A11MMEACECPA1
SCHEMBL30056275 0.96 PTGS1 (0.48) PTGS1SLC7A11MMEACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028378-A1 CHEMICALLY MODIFIED ENGINEERED SPIDER SILK PROTEINS LATVIAN INST ORGANIC SYNTHESIS (LV) 2026-01-29 — — US claimed
EP-4522636-A1 CHEMICALLY MODIFIED ENGINEERED SPIDER SILK PROTEINS Latvian Institute Of Organic Synthesis (LV) 2025-03-19 — — EP claimed
US-20240279615-A1 COMPOSITIONS COMPRISING DIPEPTIDES AND TRACE ELEMENTS EVONIK OPERATIONS GMBH (DE) 2024-08-22 — — US claimed
EP-4402246-A1 COMPOSITIONS COMPRISING DIPEPTIDES AND TRACE ELEMENTS Evonik Operations GmbH (DE) 2024-07-24 — — EP claimed
WO-2023227926-A1 CHEMICALLY MODIFIED ENGINEERED SPIDER SILK PROTEINS LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2023-11-30 — — WO claimed
EP-4166651-A1 METHODS AND COMPOSITION TO INCREASE CELLULAR GLUTATHIONE LEVEL Evonik Operations GmbH (DE) 2023-04-19 — — EP claimed
WO-2023041295-A1 COMPOSITIONS COMPRISING DIPEPTIDES AND TRACE ELEMENTS EVONIK OPERATIONS GMBH (DE) 2023-03-23 — — WO claimed
WO-2023018782-A1 METHODS TO DETERMINE CD4+ MEMORY T CELL RESPONSES TO SARS-COV-2 INFECTION OR VACCINATION ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2023-02-16 — — WO claimed
EP-4069311-A1 REACTIVE CONJUGATES Debiopharm Research & Manufacturing SA (CH) 2022-10-12 — — EP claimed
CN-101897691-A Application of isothiocyanate compounds in promoting hair growth WUXI JC PHARMACAUTICAL TECHNOLOGY INC 2010-12-01 — — CN claimed
CN-116583298-B PD-1 targeted IL-15/IL-15RαFC fusion proteins with improved properties 基因泰克公司 2026-05-12 — — CN disclosed
EP-4695412-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 — — EP disclosed
US-12527841-B2 Fibroblast growth factor-21-Fc fusion proteins NOVARTIS AG (CH) 2026-01-20 — — US disclosed
EP-4619412-A2 PEPTIDES Carocell Bio Limited (GB) 2025-09-24 — — EP disclosed
US-20250257095-A1 METHOD FOR VISIBLE LIGHT-MEDIATED CHEMICAL MODIFICATION OF POLYPEPTIDE AND PROTEIN BASED ON CYSTEINE SHANGHAI JIAO TONG UNIVERSITY (CN) 2025-08-14 — — US disclosed
US-8026054-B2 Antibodies against cells of fetal origin THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2011-09-27 — — US disclosed
CN-101897691-A Application of isothiocyanate compounds in promoting hair growth WUXI JC PHARMACAUTICAL TECHNOLOGY INC 2010-12-01 — — CN disclosed
US-20090011409-A1 Antibodies Against Cells of Fetal Origin THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLNOIS (US) 2009-01-08 — — US disclosed
EP-1819734-A2 ANTIBODIES BINDING TO CD34+/CD36+ FETAL BUT NOT TO ADULT CELLS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2007-08-22 — — EP disclosed
WO-2005123779-A2 ANTIBODIES BINDING TO CD34+/CD36+ FETAL BUT NOT TO ADULT CELLS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2005-12-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527841-B2 Fibroblast growth factor-21-Fc fusion proteins FGF23, FGFR1, FIBP PTGS1 3633/4885SLC7A11 3651/4885MME 2440/4885
US-20260028378-A1 CHEMICALLY MODIFIED ENGINEERED SPIDER SILK PROTEINS SGTA, PTMS, SCTR PTGS1 2391/4885SLC7A11 1889/4885MME 1314/4885
US-20250257095-A1 METHOD FOR VISIBLE LIGHT-MEDIATED CHEMICAL MODIFICATION OF POLYPEPTIDE AND PROTEIN BASED ON CYSTEINE PTMS, CTH, CISD1 PTGS1 1109/4885SLC7A11 143/4885MME 1398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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