SCHEMBL6681928

SCHEMBL6681928

O=P(O)(O)SCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TSHR P16473 2/20 0.47
FDPS P14324 1/20 0.45
LAP3 P28838 3/20 0.44
ANPEP P15144 3/20 0.44
CYP2C19 P33261 1/20 0.44
IDO1 P14902 3/20 0.43
HPGD P15428 1/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
ACP3 P15309 1/20 0.42
CFTR P13569 1/20 0.41
ERAP1 Q9NZ08 2/20 0.41
ERAP2 Q6P179 1/20 0.41
CA2 P00918 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6831192 0.86 ALPL (0.47) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL7079365 0.83 HPGD (0.45) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL6684403 0.81 HPGD (0.48) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL6681826 0.78 SMN1; SMN2 (0.45) ALPLALPIALPGHTTSMN1; SMN2
Benzene SCHEMBL11054611 0.78 LAP3 (0.47) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL9231165 0.78 ACHE (0.42) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL3062996 0.78 TSHR (0.44) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL3077574 0.78 TSHR (0.44) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL8469287 0.77 CA12 (0.45) ALPLALPIALPGHTTSMN1; SMN2
SCHEMBL6830707 0.77 HPGD (0.43) ALPLALPIALPGHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4406894-A PYRETHROID COMPOUND AND A PHOSPHOROTHIOLATE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1983-09-27 US claimed
US-8058414-B2 Unnatural polymerase substrates that can sustain enzymatic synthesis of double stranded nucleic acids from a nucleic acid template and methods of use Life Technologies Corporation (US) 2011-11-15 US disclosed
US-8058414-B2 Unnatural polymerase substrates that can sustain enzymatic synthesis of double stranded nucleic acids from a nucleic acid template and methods of use Life Technologies Corporation (US) 2011-11-15 US disclosed
WO-2009134469-A1 UNNATURAL POLYMERASE SUBSTRATES THAT CAN SUSTAIN ENZYMATIC SYNTHESIS OF DOUBLE STRANDED NUCLEIC ACIDS FROM A NUCLEIC ACID TEMPLATE AND METHODS OF USE LIFE TECHNOLOGIES (US) 2009-11-05 WO disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
EP-1035770-A4 USE OF FATTY ALCOHOL CARBONATES AS SOLVENTS IN AGRICULTURAL FORMULATIONS COGNIS CORP (US) 2002-07-24 EP disclosed
EP-1037528-A4 AGRICULTURAL ADJUVANT COGNIS CORP (US) 2001-06-13 EP disclosed
EP-1037528-A1 AGRICULTURAL ADJUVANT Cognis Corporation (US) 2000-09-27 EP disclosed
EP-1035770-A1 USE OF FATTY ALCOHOL CARBONATES AS SOLVENTS IN AGRICULTURAL FORMULATIONS Cognis Corporation (US) 2000-09-20 EP disclosed
WO-1999029171-A1 AGRICULTURAL ADJUVANT COGNIS CORPORATION (US) 1999-06-17 WO disclosed
WO-1999029170-A1 USE OF FATTY ALCOHOL CARBONATES AS SOLVENTS IN AGRICULTURAL FORMULATIONS COGNIS CORPORATION (US) 1999-06-17 WO disclosed
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed
US-4406894-A PYRETHROID COMPOUND AND A PHOSPHOROTHIOLATE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1983-09-27 US disclosed