Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982773 | 0.82 | PTPN1 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL8187694 | 0.81 | RAB9A (0.41) | KDM4EALDH1A1SMN1; SMN2ADRB2RAB9A | |
| SCHEMBL30397741 | 0.81 | TDP1 (0.53) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8973566 | 0.80 | NPC1 (0.56) | KDM4EALDH1A1SMN1; SMN2RAB9ARECQL | |
| SCHEMBL877094 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2RAB9ARECQLNPC1 | |
| SCHEMBL3208120 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2RAB9ARECQLNPC1 | |
| SCHEMBL10706756 | 0.78 | ADRB2 (0.65) | KDM4EALDH1A1SMN1; SMN2ADRB2RAB9A | |
| SCHEMBL18122105 | 0.78 | GRIN2D (0.45) | ALDH1A1SMN1; SMN2RAB9ARECQLNPC1 | |
| SCHEMBL13092387 | 0.77 | PTGDR2 (0.66) | ALDH1A1SMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL29997368 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2ADRB2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024558-A2 | LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-02-23 | — | — | WO | disclosed |