Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557451 | 0.84 | ALDH1A1 (0.64) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL2322100 | 0.80 | HPGD (0.54) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL7970057 | 0.80 | HPGD (0.54) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL6726793 | 0.79 | ALDH1A1 (0.58) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL16432229 | 0.79 | HPGD (0.58) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL2839336 | 0.78 | FTO (0.53) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL8386327 | 0.78 | HPGD (0.51) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL8518074 | 0.78 | HPGD (0.51) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL8385577 | 0.78 | HPGD (0.51) | ALOX12HPGDALDH1A1CYP2C9ALOX15 | |
| SCHEMBL11773203 | 0.77 | FTO (0.52) | ALOX12HPGDALDH1A1CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065548-A2 | SYNTHETIC MOLECULES FOR LABELING HISTIDINE-RICH PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-08-05 | — | — | WO | disclosed |