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Sugi Predict / Compounds / SCHEMBL2557451

SCHEMBL2557451

SCHEMBL2557451

Cc1c(C)c(C)c2c(c1C)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.64
▸ HPGD P15428 2/20 0.64
▸ ALOX12 P18054 2/20 0.64
▸ CYP2C9 P11712 1/20 0.64
▸ ALOX15 P16050 1/20 0.64
▸ BRCA1 P38398 1/20 0.64
▸ HSD17B10 Q99714 1/20 0.64
▸ FTO Q9C0B1 10/20 0.57
▸ MAPT P10636 4/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ HTT P42858 2/20 0.57
▸ SMAD3 P84022 2/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ RECQL P46063 1/20 0.57
▸ BLM P54132 1/20 0.57
▸ PRMT1 Q99873 1/20 0.57
▸ ACE2 Q9BYF1 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ LMNA P02545 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6726793 0.89 ALDH1A1 (0.58) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL16432229 0.89 HPGD (0.58) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL6682087 0.84 ALOX12 (0.54) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL1525725 0.84 FTO (0.58) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL4519856 0.82 FTO (0.63) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL4449307 0.82 FTO (0.59) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL447026 0.82 HPGD (0.51) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL486832 0.81 HPGD (0.64) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL6734651 0.80 ALDH1A1 (0.49) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL134733 0.80 ALDH1A1 (0.63) ALDH1A1HPGDALOX12CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023224949-A1 COMPOSITIONS AND METHODS RELATING TO LOOP MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) PERKINELMER U.S. LLC (US) 2023-11-23 — — WO disclosed
US-20230366038-A1 COMPOSITIONS AND METHODS RELATING TO LOOP MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) PERKINELMER U.S. LLC 2023-11-16 — — US disclosed
US-20230349007-A1 LAMP TESTING DEVICE AND METHOD USING ISOTHERMAL AMPLIFICATION OF RNA/DNA TO IDENTIFY PATHOGENS FUNDAÇÃO OSWALDO CRUZ (BR) 2023-11-02 — — US disclosed
CN-116710755-A LAMP assay devices and methods using RNA/DNA isothermal amplification for pathogen identification 奥斯瓦道·克鲁兹基金会 2023-09-05 — — CN disclosed
US-20230167513-A1 METHOS FOR RAPID DETECTION AND IDENTIFICATION OF VIRAL NUCLEIC ACIDS NYAN DOUGBEH CHRIS (US) 2023-06-01 — — US disclosed
US-20220127658-A1 SYSTEMS AND METHODS FOR ULTRA-SPECIFIC AND ULTRA-SENSITIVE NUCLEIC ACID DETECTION WAYNE STATE UNIVERSITY 2022-04-28 — — US disclosed
US-20220010365-A1 REAL-TIME PCR FOR THE DETECTION OF PATHOGENS THE GOVERNMENT OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH AND HUMAN SERVICES (US) 2022-01-13 — — US disclosed
EP-3929310-A1 METHODS AND MEANS FOR CORONA VIRUS NUCLEIC ACID DETECTION FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) 2021-12-29 — — EP disclosed
EP-3929311-A2 METHODS AND MEANS FOR CORONA VIRUS NUCLEIC ACID DETECTION Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-12-29 — — EP disclosed
US-11162144-B2 Real-time PCR for the detection of pathogens THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2021-11-02 — — US disclosed
US-20150086987-A1 REAL-TIME PCR FOR THE DETECTION OF PATHOGENS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2015-03-26 — — US disclosed
WO-2014186734-A2 METHODS AND COMPOSITIONS FOR DETECTION OF LEGIONELLA THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2014-11-20 — — WO disclosed
WO-2014144197-A1 STEREODYNAMIC CHEMOSENSORS GEORGETOWN UNIVERSITY (US) 2014-09-18 — — WO disclosed
WO-2014005038-A1 NUCLEASE PROTECTION METHODS FOR DETECTION OF NUCLEOTIDE VARIANTS HTG MOLECULAR DIAGNOSTICS, INC. (US) 2014-01-03 — — WO disclosed
WO-2013187958-A1 METHODS AND COMPOSITIONS FOR DETECTION OF LEGIONELLA THE GOVERN. OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH AND HUMAN SERVICES (US) 2013-12-19 — — WO disclosed
US-20130331285-A1 METHODS AND COMPOSITIONS FOR DETECTION OF LEGIONELLA The Government of the United Sates of America as represented by the Secretary of the Department of (US) 2013-12-12 — — US disclosed
WO-2013165537-A1 REAL-TIME PCR FOR THE DETECTION OF PATHOGENS THE GOVERNMENT OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2013-11-07 — — WO disclosed
US-20130065787-A1 REAL TIME PCR ASSAY FOR DETECTION OF BACTERIAL RESPIRATORY PATHOGENS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION 2013-03-14 — — US disclosed
EP-2558596-A2 REAL TIME PCR ASSAY FOR DETECTION OF BACTERIAL RESPIRATORY PATHOGENS The Government Of The United States Of America As Reresented By The Secretary Of The Department Of Health & Human Services (US) 2013-02-20 — — EP disclosed
WO-2011133433-A2 REAL TIME PCR ASSAY FOR DETECTION OF BACTERIAL RESPIRATORY PATHOGENS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION (US) 2011-10-27 — — WO disclosed