Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.42 |
| ▸ | IDH2 | P48735 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478998 | 0.82 | MEN1 (0.50) | TRPV1IDH2RAB9ALMNANPC1 | |
| SCHEMBL6479006 | 0.77 | FOLH1 (0.45) | TRPV1SLC16A3RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6490134 | 0.76 | MGLL (0.65) | TRPV1MEN1KMT2AMAPT | |
| SCHEMBL23086244 | 0.76 | IDH2 (0.50) | IDH2RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL31253047 | 0.74 | MAPT (0.51) | RAB9ALMNANPC1SMN1; SMN2TDP1 | |
| SCHEMBL6684180 | 0.73 | TRPV1 (0.63) | TRPV1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6480620 | 0.72 | MGLL (0.51) | TRPV1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4688032 | 0.72 | ALDH1A1 (0.49) | TRPV1SLC16A3LMNAALDH1A1GAA | |
| SCHEMBL31253065 | 0.71 | LTB4R (0.48) | TDP1MEN1KMT2AALDH1A1LTB4R | |
| SCHEMBL27849340 | 0.71 | KCNK3 (0.56) | SLC16A3RAB9ALMNANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461311-A2 | UREA DERIVATIVES AS VR1-ANTAGONISTS | Bayer HealthCare AG (DE) | 2004-09-29 | — | — | EP | claimed |
| WO-2003055848-A2 | UREA DERIVATIVES AS VR1- ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | claimed |