Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LIG1 | P18858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.84 | HPGD (0.60) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.84 | HPGD (0.60) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL5513156 | 0.81 | ADRA2A (0.44) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL21736890 | 0.81 | ADRB2 (0.43) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL4146222 | 0.80 | KDM4E (0.54) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL3800333 | 0.78 | HPGD (0.55) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL7764770 | 0.78 | HPGD (0.55) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL14977791 | 0.78 | HPGD (0.50) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL7711833 | 0.77 | MAPT (0.47) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL21719009 | 0.77 | ADRA2A (0.41) | HPGDTSHRMAPK1HSD17B10LIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7296576-B2 | Polymers for enhanced solubility of nanomaterials, compositions and methods therefor | ZYVEX PERFORMANCE MATERIALS, LLC (US) | 2007-11-20 | — | — | US | claimed |
| US-20060041104-A1 | Polymers for enhanced solubility of nanomaterials, compositions and methods therefor | ZYVEX CORPORATION (US) | 2006-02-23 | — | — | US | claimed |
| US-4992568-A | One step cyclization of ortho-iodoaryl allyl ether in presence of palladium catalyst | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1991-02-12 | — | — | US | claimed |
| EP-4298135-B1 | BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20240158542-A1 | BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-16 | — | — | US | disclosed |
| EP-4298135-A1 | BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS | Dow Global Technologies LLC (US) | 2024-01-03 | — | — | EP | disclosed |
| CN-116897168-A | Bis-phenoxy-ether ligands for Group IV polyolefin catalysis | 陶氏环球技术有限责任公司 | 2023-10-17 | — | — | CN | disclosed |
| WO-2022183005-A1 | BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-09-01 | — | — | WO | disclosed |
| EP-3939962-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-01-19 | — | — | EP | disclosed |
| EP-3939962-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |
| WO-2012035171-A2 | NEW COMPOUNDS | KANCERA AB (SE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012024564-A1 | FLUOROALKYLATION METHODS AND REAGENTS | THE BOARD OF TRUSTESS OF THE UNIVERSITY OF ILLINOIS (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20100305173-A1 | HYDROXYETHYLAMINO SULFONAMIDE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305173-A1 | HYDROXYETHYLAMINO SULFONAMIDE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| CN-101641335-A | Amino-5-[substituted-4-(difluoromethoxy)phenyl]-5- phenylimidazolone compounds as ss-secretase inhibitors | WYETH CORP US | 2010-02-03 | — | — | CN | disclosed |
| EP-2137161-A1 | AMINO-5-[SUBSTITUTED-4-(DIFLUOROMETHOXY)PHENYL]-5- PHENYLIMIDAZOLONE COMPOUNDS AS ß-SECRETASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-12-30 | — | — | EP | disclosed |
| US-20090042964-A1 | AMINO-5-[SUBSTITUTED-4-(DIFLUOROMETHOXY)PHENYL]-5-PHENYLIMIDAZOLONE COMPOUNDS AS BETA-SECRETASE INHIBITORS | WYETH (US) | 2009-02-12 | — | — | US | disclosed |
| WO-2008115552-A1 | AMINO-5-[SUBSTITUTED-4-(DIFLUOROMETHOXY)PHENYL]-5- PHENYLIMIDAZOLONE COMPOUNDS AS ß-SECRETASE INHIBITORS | WYETH (US) | 2008-09-25 | — | — | WO | disclosed |
| US-4992568-A | One step cyclization of ortho-iodoaryl allyl ether in presence of palladium catalyst | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1991-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305173-A1 | HYDROXYETHYLAMINO SULFONAMIDE DERIVATIVES | STS, PRSS1, PRSS3 | HPGD 1821/4885TSHR 4797/4885MAPK1 4049/4885 |
| US-20090042964-A1 | AMINO-5-[SUBSTITUTED-4-(DIFLUOROMETHOXY)PHENYL]-5-PHENYLIMIDAZOLONE COMPOUNDS AS BETA-SECRETASE INHIBITORS | BACE1, BACE2, APP | HPGD 4162/4885TSHR 4819/4885MAPK1 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.