Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6679110 | 0.99 | ALDH1A1 (0.40) | GAAALDH1A1ALOX12LMNAHPGD | |
| SCHEMBL6676422 | 0.84 | ALDH1A1 (0.42) | GAAALDH1A1ALOX12LMNAHPGD | |
| Hydrochloric Acid SCHEMBL6675363 | 0.82 | ALDH1A1 (0.41) | GAAALDH1A1ALOX12LMNAHPGD | |
| SCHEMBL6680198 | 0.81 | ALDH1A1 (0.43) | GAAALDH1A1ALOX12LMNAHPGD | |
| SCHEMBL6675321 | 0.81 | ALDH1A1 (0.40) | GAAALDH1A1ALOX12LMNAHPGD | |
| Hydrochloric Acid SCHEMBL7240792 | 0.80 | ALDH1A1 (0.40) | GAAALDH1A1ALOX12LMNAHPGD | |
| SCHEMBL6674481 | 0.72 | ALDH1A1 (0.40) | GAAALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL6680201 | 0.72 | CACNA1C (0.46) | ALDH1A1ALOX12LMNAHPGDKMT2A | |
| SCHEMBL6676761 | 0.72 | POLB (0.35) | GAAALDH1A1LMNAHPGDCACNA1C | |
| SCHEMBL6676347 | 0.72 | ALDH1A1 (0.39) | GAAALDH1A1KMT2AMEN1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |