Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675316 | 0.85 | PNMT (0.41) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| SCHEMBL6676422 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| Hydrochloric Acid SCHEMBL6675363 | 0.84 | ALDH1A1 (0.41) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| Hydrochloric Acid SCHEMBL6674248 | 0.84 | PNMT (0.40) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| SCHEMBL6676762 | 0.81 | GLS (0.35) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| SCHEMBL6676189 | 0.81 | CACNA1C (0.33) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| Hydrochloric Acid SCHEMBL6680715 | 0.80 | GLS (0.35) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| Hydrochloric Acid SCHEMBL6679054 | 0.80 | CACNA1C (0.33) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| SCHEMBL6676327 | 0.77 | TAAR1 (0.41) | ALDH1A1GAAMAPTSMN1; SMN2PKM | |
| SCHEMBL6680198 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAACACNA1CSCN5AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |