Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676422 | 0.88 | ALDH1A1 (0.42) | ALDH1A1GAALMNAHPGDALOX12 | |
| Hydrochloric Acid SCHEMBL6675363 | 0.87 | ALDH1A1 (0.41) | ALDH1A1GAALMNAHPGDALOX12 | |
| SCHEMBL6676327 | 0.87 | TAAR1 (0.41) | ALDH1A1GAATAAR1MAPT | |
| Hydrochloric Acid SCHEMBL6674891 | 0.85 | TAAR1 (0.40) | ALDH1A1GAATAAR1MAPT | |
| SCHEMBL6682250 | 0.81 | GAA (0.41) | ALDH1A1GAALMNAHPGDALOX12 | |
| SCHEMBL6675321 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAALMNAHPGDALOX12 | |
| Hydrochloric Acid SCHEMBL6679110 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAALMNAHPGDALOX12 | |
| Hydrochloric Acid SCHEMBL7240792 | 0.79 | ALDH1A1 (0.40) | ALDH1A1GAALMNAHPGDALOX12 | |
| SCHEMBL6676347 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GAACACNA1CSCN5AMAPT | |
| SCHEMBL6675316 | 0.77 | PNMT (0.41) | ALDH1A1GAALMNAHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |