Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166809 | 0.85 | EGFR (0.55) | PTGS2MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL30542066 | 0.84 | MEN1 (0.43) | PTGS2MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5665323 | 0.84 | MEN1 (0.43) | PTGS2MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7276190 | 0.80 | KDM4E (0.56) | PTGS2PTGS1PKMMEN1KMT2A | |
| SCHEMBL15332438 | 0.77 | PTGS2 (0.58) | PTGS2PTGS1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6684009 | 0.73 | KDM4E (0.46) | PTGS2PTGS1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6682810 | 0.73 | KDM4E (0.46) | PTGS2PTGS1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6681781 | 0.73 | KDM4E (0.46) | PTGS2PTGS1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6679627 | 0.73 | L3MBTL1 (0.45) | PTGS2PTGS1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7267915 | 0.72 | PTGS2 (0.49) | PTGS2PTGS1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474390-A1 | INDOLE DERIVATIVES SUBSTITUTED WITH LONG-CHAIN ALCOHOLS AND MEDICAMENTS CONTAINING THEM | Meiji Dairies Corporation (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068741-A1 | INDOLE DERIVATIVES SUBSTITUTED WITH LONG-CHAIN ALCOHOLS AND MEDICAMENTS CONTAINING THEM | MEIJI DAIRIES CORPORATION (JP) | 2003-08-21 | — | — | WO | disclosed |